The principal cytochrome P450 isoenzyme concerned seems to generally be CYP2E1, with CYP1A2 and CYP3A4 as extra pathways. Around eighty five% of the oral dose appears while in the urine within just 24 hrs of administration, most because the glucuronide conjugate, with compact amounts of other conjugates and unchanged drug [see OVERDOSAGE] for toxic… Read More